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What are the Most Common Symptoms of Appendicitis? The first set of symptoms which most people who have suffered from appendicitis have reported is a general abdominal pain in some cases this symptom is preempted or complemented by a loss of appetite... The first set of symptoms which most people who have suffered from appendicitis have reported is a general abdominal pain in some cases this symptom is preempted or complemented by a loss of appetite... Appendicitis - What is it and What Causes it? Simply put appendicitis is an inflammation of the appendix. The appendix is a thin close-ended tube which it is attached to the first part of the colon, is part of the colon produces mucus which is transferred into the cecum. Simply put appendicitis is an inflammation of the appendix. The appendix is a thin close-ended tube which it is attached to the first part of the colon, is part of the colon produces mucus which is transferred into the cecum.