Cirrhosis of the liver : Diseases - By: Navtej Kohli MD

Navtej Kohli bringing the information of Cirrhosis of the liver and he writes after doing the deep research into latest medical journal .Cirrhosis is the end result of many liver diseases that occur due to abnormal functioning of liver in human body. Hepatic cirrhosis can occur at any stage of life.Online health and disease are widely discussed topics now a days, people usually eager to know how to make their life healthy. Navtej Kohli discovered Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules.

Causes:

Cirrhosis is caused due to many reasons. Sometimes, a patient suffers from more than one cause. Chronic alcoholism and hepatitis C are the most common causes. Other than these factors, non-alcoholic steatohepatitis, primary biliary cirrhosis, autoimmune hepatitis and congenital abnormalities may result in cirrhosis of liver.

Clinical Features:

These vary to a wider range and most of the times the disease remains asymptomatic throughout life or is incidentally diagnosed during surgery. The general features include weakness, fatigue, muscle cramps, weight loss, and non-specific digestive symptoms such as anorexia, nausea, vomiting, upper abdominal discomfort and gaseous abdominal distension.
Other specific clinical features that may arise are: hepatomgaly, jaundice, ascites, and portal hypertension along with splenomegaly, collateral vessels and variceal bleeding. These features are however present at the advanced stage of the disease.

Diagnosis:

Biochemical investigations are carried out to diagnose the disease. Liver function tests viz. AST, ALT, bilirubin, and albumin are advised. Prothrombin factor and clotting time etc are also checked. Ultrasonography is the basic test to perform which is generally followed by CT scan, to assess the structural changes and damage done to the liver.
Biopsy is avoided in cirrhosis of liver.

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Complications:

The disease is severe in nature and the prognosis is poor. It may lead to portal hypertension, ascites, hepatic encephalopathy, renal failure, infection of various organs, and hepatocellular carcinoma.

Management:

Cirrhosis is an irreversible stage of liver dysfunction. The structural changes are not reversible and only further damage to the liver can be avoided. The underlying cause is treated. In the absence of complications, high protein diet is recommended. Fat intake is also not restricted depending upon the condition of patient.
Metabolic drugs are generally prescribed but with extreme caution as a cirrhotic patient may develop toxic reactions to the treatment.
Liver transplant is an open option in patients whose liver fail to recuperate.

About the Author

Navtej Kohli MD navtej kohli md wants to make the health as his vision, he launched an Online disease and health encyclopedia as well gives the reader a unique opportunity to discuss the health issue via discussion forum and health reviews section.

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